Endocrine Abstracts

Introduction: The metabolic syndrome (MS) is a frequent complication of the obstructive sleep apnea hypopnea syndrome (OSAHS). Its predictive factors have to be known by the doctors setting in charge patients with OSAHS. The aim of this study was to determine the prevalence of the MS and its predictive factors in Tunisian patients with OSAHS.Methods: A retrospective study including 181 patients with OSAHS from the respiratory D department at the Abderrah...

Introduction: 11β-Hydroxylase deficiency (11β-OHD), caused by CYP11B1 mutations, is characterized by hyporeninemic, hypokalemic hypertension and hyperandrogenism. We studied the mutations of CYP11B1 gene in two patients with classic 11β-OHD.Observations: We present the first case of a 23 year old boy with preliminary diagnosis of 21 β-OHD diagnosed at the age of 10. The patient presented with hypertension and hypokalemia which were ag...

Introduction: Cardiovascular complications are well known in type 2 diabetes with other factors of cardiovascular disease. Recently, with the intensive treatment of type 1 diabetes, many studies have focused on macrovascular complications in type 1 diabetes. The aim of our study was to determine the long-term cardiovascular risk factors and macrovascular complications in type 1 diabetic patients.Patients and methods: A retrospective study involving 45 pa...

Gastrointestinal stromal tumour (GIST) is now defined as a specific, KIT-expressing and KIT-signalling driven mesenchymal tumour of the gastrointestinal (GI) tract. We report a case of stromal tumour revealed by prolonged fever and skin lesions associated with primary hyperparathyroidism and pituitary adenoma.Observation: We present the case of a 59-year-old patient admitted for prolonged fever with inflammatory syndrome and latte tasks cutaneous lesions...